“(Lack of exercise) results in a vicious cycle that increases oxidative stress and reduces metabolic flexibility and perpetuates the disease state. In contrast, hormetic stimuli can induce an anti-inflammatory phenotype… leading to greater biological fitness and improved functional longevity. The links between obesity, the metabolic syndrome, diabetes, vascular disease and even cancer, are now all too clear.”
Sitting Around Makes You Want to Sit Around; Challenging Yourself Leads to Fitness and Longevity
